The research in my lab centers on structure-function relationships of metallomolecules involved in redox sensing, metal homeostasis and detoxification. My current research focuses on the metalloproteins involved in biotic and abiotic stress sensing or detoxification. Diverse tools will be utilized in my lab, including synchrotron-radiation based X-ray diffraction, X-ray absorption spectroscopy, as well as biochemical techniques and computational modeling.
Education
- Ph D, University of Saskatchewan, 2009
- MS, University of Victoria, 2000
- BS, Jilin University, 1997
Courses
- BIOC 932, Proteins, Fall 2020
- BIOC 433H, Honors: Inquiry-based Biochemistry Laboratory, Fall 2019
Grants
- Cryo-Electron Microscopy, NSF, February 2021
- CAREER:Fe-S Cluster-Based NO Sensor, NSF, July 2019
Honors
- NSF CAREER Award, NSF, 2019
- Center of Environmental Microbial Interactions fellowship, California Institute of Technology, 2013
- Natural Sciences and Engineering Research Council of Canada Postdoctoral Fellowship, Natural Sciences and Engineering Research Council of Canada, 2009
Papers
- A sulfur-based transport pathway in Cu+-ATPases, EMBO Rep
- Characterization of an Fe≡N-NH2 Intermediate Relevant to Catalytic N2 Reduction to NH3, J Am Chem Soc
- Nitrogenase MoFe protein from Clostridium pasteurianum at 1.08 A resolution: comparison with the Azotobacter vinelandii MoFe protein, Acta Crystallogr D Biol Crystallogr
- A polar copper-boron one-electron sigma-bond, J Am Chem Soc
- The sixteenth iron in the nitrogenase MoFe protein, Angew Chem Int Ed Engl
- Tracing copper-thiomolybdate complexes in a prospective treatment for Wilson’s disease, Biochemistry